Calpains for dummies: What you need to know about the calpain family

نویسندگان

چکیده

This review was written in memory of our late friend, Dr. Hiroyuki Sorimachi, who, following the steps his mentor Koichi Suzuki, a pioneer calpain research, has made tremendous contributions to field. During career, Hiro also wrote several reviews on calpain, last which, published 2016, comprehensive. In this manuscript, we decided put together with basic information novice may need know about calpains. We tried avoid similarities previous and reported most significant new findings, at same time highlighting Hiro's The will cover short history discovery, presentation family, life from transcription activity, human diseases caused by mutations therapeutic perspectives.

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ژورنال

عنوان ژورنال: Biochimica Et Biophysica Acta - Proteins And Proteomics

سال: 2021

ISSN: ['0926-6569', '1878-1454', '1878-223X', '0167-4838', '0005-2795', '1570-9639', '1879-2952', '0926-6593', '1878-2248', '1879-2588', '0005-2744']

DOI: https://doi.org/10.1016/j.bbapap.2021.140616